Stock Market LIVE Updates: Domestic indices trade lower at pre-open; most Asian markets down

Tokyo stocks opened lower Wednesday with investors taking cues from a cut to profit estimates by US retail giant Walmart, which helped drag down US markets. The benchmark Nikkei 225 index slipped 0.44 percent, or 120.43 points, to 27,534.78 in early trade, while the broader Topix index fell 0.31 percent, or 5.98 points, to 1,937.19.